Asmaplex

Asmaplex

Manufacturer:

AD-Drugstel

Distributor:

AD-Drugstel
Full Prescribing Info
Contents
Guaifenesin, salbutamol.
Description
Each 5 mL (1 teaspoonful) contains: Guaifenesin 50 mg, Salbutamol (as sulfate) 1 mg.
Action
Pharmacology: Pharmacokinetics: Guaifenesin is absorbed from the gastrointestinal tract. It is metabolized and then excreted in the urine.
Salbutamol is rapidly absorbed from the gastrointestinal tract. It is subject to first-pass metabolism in the liver and possibly in the gut wall; the main metabolite is an inactive sulfate conjugate. Salbutamol is rapidly excreted in the urine as metabolites and uncharged drug, there is some excretion in the feces. The plasma half-life of salbutamol has been estimated to range from 4 to 6 hours.
Indications/Uses
Respiratory disorders complicated by bronchospasm and excessive secretion of tenacious mucus, bronchial asthma, chronic bronchitis and emphysema.
Dosage/Direction for Use
Children: 2 to 6 years old: 2.5 mL - 5 mL (½ teaspoon - 1 teaspoonful); 7 to 12 years old: 5 mL - 10 mL (1 teaspoonful - 2 teaspoonfuls).
Adult: 15 mL (1 tablespoonful).
To be taken every three to four times daily or as prescribed by a physician.
Special Precautions
Asmaplex should not be given to patients with known history of peptic ulcer or gastritis. Its concurrent use with other xanthine derivatives is not advised.
Adverse Reactions
The most common adverse reactions are gastrointestinal irritation and CNS stimulation.
Drug Interactions
Concomitant administration of salbutamol and other beta2 agonists with corticosteroids, diuretics, or xanthines increase the risk of hypokalemia, and monitoring of potassium concentrations is recommended in severe asthma, where such combination therapy is the rule.
Storage
Store at temperatures not exceeding 30°C.
ATC Classification
R05CA10 - combinations ; Belongs to the class of expectorants. Used in the treatment of wet cough.
Presentation/Packing
Syr 60 mL.
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