Aspidon

Aspidon Dosage/Direction for Use

risperidone

Manufacturer:

Torrent

Distributor:

Torrent
Full Prescribing Info
Dosage/Direction for Use
Schizophrenia: When switching from other antipsychotics, where medically appropriate, gradual discontinuation of the previous treatment while Risperidone therapy is initiated is recommended.
Adults: Risperidone may be given once or twice daily. Treatment should be started with 2 mg/day, whether for acute or chronic condition. The dosage may be increased to 4 mg/day on the second day.
Some patients, such as first episode patients, may benefit from a slower rate of titration. From then on, the dosage can be maintained unchanged, or further individualized, if needed. Most patients will benefit from daily doses between 4 and 6 mg/day although in some, an optimal response may be obtained at lower doses. Doses above 10 mg/day generally have not been shown to provide additional efficacy to lower doses and may increase the risk of extrapyramidal symptoms.
Doses above 10 mg/day should only be used in individual patients if the benefit is considered to outweigh the risk. Doses above 16 mg/day have not been extensively evaluated for safety and therefore should not be used.
Elderly & Patients with renal and liver disease: A starting dose of 0.5 mg b.d. is recommended. This dosage can be individually adjusted with 0.5 mg b.d. increments to 1 to 2 mg b.d. Risperidone should be used with caution in this group of patients until further experience is gained.
Children: Use of Risperidone for schizophrenia in children aged less than 15 years has not been formally evaluated.
Bipolar Mania: Adults: Risperidone should be administered on a once daily schedule, starting with 2 mg. Dosage adjustments, if indicated, should occur at intervals of not less than 24 hours and in dosage increments of 1 mg per day. A dosing range between 1 and 6 mg per day is recommended.
As with all symptomatic treatments, the continued use of Risperidone must be evaluated and justified on an ongoing basis.
Elderly & Patients with renal and liver disease: A starting dose of 0.5 mg b.d. is recommended. This dosage can be individually adjusted with 0.5 mg b.d. increments to 1 to 2 mg b.d. Risperidone should be used with caution in this group of patients until further experience is gained.
Combined use with mood stabilisers: There is limited information on the combined use of Risperidone with carbamazepine in bipolar mania. Carbamazepine has been shown to induce the metabolism of risperidone producing lower plasma levels of the antipsychotic fraction of Risperidone. It is therefore not recommended to co-administer Risperidone with carbamazepine in bipolar mania patients until further experience is gained. The combined use with lithium or valproate does not require any adjustment of the dose of Risperidone.
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