The usual initial dose of atracurium besilate for adults and children over one month of age is 300 to 600 μg per kg body weight by intravenous injection. Subsequent doses of 100 to 200 mcg per kg may be given as necessary, typically after 15 to 25 minutes. It is recommended that in patients with cardiovascular disease that initial dose should be administered over a period of 60 seconds.
Atracurium besilate may also be given by continuous intravenous infusion at a rate of 5 to 10 mcg per kg per minute to maintain neuromuscular block during prolonged procedures. Somewhat higher infusion rates may be used in patients undergoing controlled ventilation in intensive care.
Or as prescribed by the physician.