Avamax

Avamax

atorvastatin

Manufacturer:

Therapharma

Distributor:

United Lab
Concise Prescribing Info
Contents
Atorvastatin Ca
Indications/Uses
Reduces LDL-cholesterol, apolipoprotein B & triglycerides; increases HDL-cholesterol in the treatment of hyperlipidemias. Adjunct therapy in patients w/ homozygous familial hypercholesterolemia who have some LDL-receptor function. Primary prophylaxis of CV events in patients w/ multiple risk factors.
Dosage/Direction for Use
Dose range: 10-80 mg once daily. Doses may be given any time of the day. Dosage should be individualized according to baseline LDL-cholesterol levels, goal of therapy & patient response. Primary hypercholesterolemia & combined hyperlipidemia 10 mg once daily. Homozygous familial hypercholesterolemia 10-80 mg daily.
Administration
May be taken with or without food.
Contraindications
Active liver disease or unexplained persistent elevations of serum transaminases. Pregnancy, women of childbearing potential, lactation.
Special Precautions
Perform liver function tests & monitor for creatine phosphokinase & transaminase elevations. Avoid alcohol consumption. Temporarily discontinue therapy in patients w/ an acute, serious condition suggestive of a myopathy or renal failure secondary to rhabdomyolysis.
Adverse Reactions
Chest pain, face edema, fever, neck rigidity, malaise, photosensitivity reaction, generalized edema. Nausea & vomiting, gastroenteritis, colitis, gastritis, dry mouth. Arthritis, leg cramps, bursitis, tenosynovitis, myasthenia, tendinous contracture, myositis. Anaphylaxis, angioneurotic edema, bullous rashes (including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis), rhabdomyolysis & fatigue.
Drug Interactions
Cyclosporin, fibric acid derivatives, erythromycin, azole antifungals or niacin. Oral antacid susp containing Mg & Al hydroxide, colestipol, digoxin. PIs, diltiazem HCl & grapefruit juice. Norethisterone & ethinylestradiol.
ATC Classification
C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.
Presentation/Packing
Form
Avamax FC tab 20 mg
Packing/Price
100's (P3,090/box, P31/film-coated tab)
Form
Avamax FC tab 40 mg
Packing/Price
100's (P3,745/box, P37/film-coated tab)
Form
Avamax FC tab 80 mg
Packing/Price
30's (P1,123.51/box, P37.45/film-coated tab)
Form
Avamax FC tab 10 mg
Packing/Price
100's (P2,625/box, P26/film-coated tab)
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