Bayer Aspirin 100 mg

Bayer Aspirin 100 mg





Concise Prescribing Info
Acetylsalicylic acid
Reduces the risk of morbidity & mortality in patients w/ suspected or previous MI, in people w/ CV risk factors (DM, hyperlipidemia, HTN, obesity, smoking, old age); stroke in patients w/ transient ischemic attack (TIA); prevention of thromboembolism after vascular surgery interventions eg, PTCA, CABG, carotid endarterectomy, arteriovenous shunts; reducing the risk of morbidity & death in patients w/ stable & unstable angina pectoris; prophylaxis of DVT & lung embolism after long-term immobilization (eg, after major surgery). Secondary prevention of stroke.
Dosage/Direction for Use
Antithrombotic 1 tab each day. Acute MI 162-325 mg as soon as MI is suspected. Maintenance dose: 162-325 mg daily, continued for 30 days post-infarction. Consider further therapy for prevention of recurrent MI after 30 days. Previous MI/secondary prevention of stroke/prevention of thromboembolism after vascular surgery or interventions/patient w/ TIA; or stable & unstable angina pectoris 81-325 mg/day. Prophylaxis of DVT & lung embolism 81-200 mg/day or 300-325 mg every other day. Reducing the risk of 1st MI 81-100 mg/day or 300-325 mg every other day. Patient w/ liver or kidney function disturbances Reduce the dose or the interval between doses increased.
Should be taken with food: Take immediately after meals.
Hypersensitivity to aspirin & other salicylates. History of salicylate-induced asthma, notably NSAIDs. Active gastric or duodenal ulcers, hemorrhagic diathesis, severe renal or cardiac failure. Combination w/ methotrexate at doses of ≥15 mg/wk; last trimester of pregnancy.
Special Precautions
Poisoning must be watched for in the elderly & above all in young childn (therapeutic dose or frequent accidental poisoning) in whom it may be fatal. 1st & 2nd trimester of pregnancy, breastfeeding when using high doses (>300 mg/daily). In the presence of concomitant treatment w/ anticoagulants (eg, coumarin derivatives or heparin - except low-dose heparin therapy), impaired renal or hepatic function, severe liver or kidney damage; hypersensitivity to anti-inflammatory drugs or antirheumatic drugs of other allergens; patients suffering from severe G6PD deficiency. May induce hemolysis or hemolytic anemia. May attenuate inhibitory effect on platelet aggregation w/ some NSAIDs (eg, ibuprofen & naproxen). Possibility of Reye's syndrome in childn & adolescents w/ febrile diseases using medicinal products containing aspirin; patients w/ bronchial asthma, chronic bronchoconstrictive (obstructive) resp disease, hay fever, or nasal polyps may react to non-steroidal analgesics w/ asthma attacks, Quincke's edema (localized swelling of the skin or mucosa), or urticaria more frequently than other patients; may lead to increased bleeding tendency during & after surgical operations (including minor surgeries eg, dental extractions). Can trigger gout in patients who already tend to have low acid uric excretion.
Adverse Reactions
Hypersensitivity reactions (eg, urticaria, skin reactions, anaphylactic reactions, asthma, Quincke's edema); dizziness & tinnitus which are usually indicative of overdose; bleeding risk; abdominal pain, heartburn, nausea, diarrhea, vomiting; evident (hematemesis, melena) or occult GI hemorrhage which may cause Fe deficiency anemia; anemia (eg, hemorrhagic, hemolytic), gastro-duodenal ulcer & perforation; isolated cases of liver function disturbances, hypoglycemia, hemorrhage.
Drug Interactions
Methotrexate, NSAIDs, anticoagulants, thrombolytics & other antiplatelets; uricosurics, digoxin, antidiabetics, diuretics, systemic glucocorticoids except hydrocortisone, ACE inhibitors, valproic acid, alcohol.
MIMS Class
Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
ATC Classification
B01AC06 - acetylsalicylic acid ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Bayer Aspirin 100 mg tab
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