Benzoyl peroxide

Generic Medicine Info
Indications and Dosage
Adult: As 2.5-10% preparation: Apply 1-2 times daily after cleansing, may gradually increase to tid if needed. Start w/ lower strength preparations. As cleanser: Wash 1-2 times daily.
Child: ≥12 yr Same as adult dose.

Decubitus/stasis ulcers
Adult: As 20% lotion: Apply 8-12 hrly.
Special Precautions
Childn. Pregnancy and lactation.
Adverse Reactions
Dry skin, erythema, skin exfoliation and burning sensation, pruritus, irritation, allergic contact dermatitis, swelling face.
Potentially Fatal: Rarely, hypersensitivity reactions.
Patient Counseling Information
Avoid unnecessary sun exposure. May cause discolouration of hair and dyed fabrics.
Perform sensitivity test before using the product for the 1st time.
Symptom: Severe irritation: Management: Symptomatic treatment.
Drug Interactions
Decreased efficacy and increase irritation if concomitantly administered w/ tretinoin, isotretinoin and tazarotene. Temporary skin and facial hair discolouration (yellow/orange) w/ sulphonamide-containing products.
Description: Benzoyl peroxide has mild keratolytic effect and antimicrobial activity due to release of free-radical oxygen which oxidizes bacterial protein. It is active against Staphylococcus epidermidis and Propionibacterium acnes.
Absorption: Approx 5% is absorbed through the skin.
Metabolism: Metabolised in the skin to benzoic acid.
Excretion: Via urine.
Chemical Structure

Chemical Structure Image
Benzoyl Peroxide

Source: National Center for Biotechnology Information. PubChem Database. Benzoyl peroxide, CID=7187, (accessed on Jan. 21, 2020)

Store between 15-30˚C.
ATC Classification
D10AE01 - benzoyl peroxide ; Belongs to the class of topical peroxide preparations used in the treatment of acne.
Anon. Benzoyl Peroxide. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 06/06/2016.

Benzoyl Peroxide 10% Gel (Axia Medical Solutions, LLC). DailyMed. Source: U.S. National Library of Medicine. Accessed 06/06/2016.

Buckingham R (ed). Benzoyl Peroxide. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 06/06/2016.

Joint Formulary Committee. Benzoyl Peroxide. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. Accessed 06/06/2016.

Disclaimer: This information is independently developed by MIMS based on Benzoyl peroxide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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