Except under special circumstances, this medication should not be used when the following medical problem exists: Coronary artery bypass graft (CABG) surgery (Meloxicam is contraindicated for the treatment of peri-operative pain in the setting of CABG) surgery. Hypersensitivity to Meloxicam. Nasal polyps associated with bronchospasm, Aspirin-induced (high risk of severe allergic reaction). Previous allergic/anaphylactic reaction to aspirin or other NSAIDs.
Risk-benefit should be considered when the following medical problems exist: Gastrointestinal bleeding, active, or pre-existing. Peptic ulcer disease, active or Risk factors for CV disease (may be at greater risk of serious CV thrombotic events; lowest effective dose of Meloxicam for shortest duration should be used with physicians and patients remaining alert for development of signs and symptoms of such events). Renal function impairment, severe (long-term studies have not been done in patients with severe renal function impairment; use of Meloxicam is not recommended in these patients; however, if Meloxicam is used in patients with severe renal impairment, close monitoring is recommended).