Allergic or anaphylactoid reactions, loss of consiousness, collapse & hypotension. Avoid in patients w/ hepatic dysfunction where Fe overload is a precipitating factor, in particular Porphyria cutanea tarda (PCT). Periodic monitoring of hematologic & anti-anemia parameters (Hb, hematocrit, serum ferritin & transferrin saturation). W/held therapy in patients w/ evidence of Fe overload. Acute or chronic infection. Paravenous leakage. Lactation, Childn. Elderly.