2-4 g/day as IV/IM every 12 hr in equally divided doses. Severe or refractory infections
8 g as IV every 12 hr in equally divided doses. Childn
40-80 mg/kg/day every 6-12 hr. Serious or refractory infections
240 mg/kg/day in 2-4 equally divided doses. Neonates
In the 1st wk of life, administer every 12 hr. Max of 80 mg/kg/day. Renal impairment CrCl 15-30 mL/min
Max of 1-g sulbactam every 12 hr, <15 mL/min
Max of 500 mg sulbactam every 12 hr.