Brexen

Brexen

celecoxib

Manufacturer:

ADP Pharma

Distributor:

Metro Drug

Marketer:

Seville Pharma
Concise Prescribing Info
Contents
Celecoxib
Indications/Uses
Relief of the signs & symptoms of OA & RA in adults. Adjunct for reduction of number of adenomatous colorectal polyps in familial polyposis. Management of acute pain & dysmenorrhea.
Dosage/Direction for Use
OA 200 mg daily as a single dose or in 2 divided doses. A dose of 200 mg bid may be used if necessary. RA 100-200 mg bid. Ankylosing spondylitis Initially 200 mg daily as a single dose or in 2 divided doses. Pain & dysmenorrhea Initially 400 mg followed by 200 mg, if necessary, on the 1st day & 200 mg bid thereafter.
Administration
May be taken with or without food: Dose for OA/RA may be given w/ or w/o meals.
Contraindications
History of CVA, MI, CABG, uncontrolled HTN, CHF NYHA II-IV.
Special Precautions
Not to be used after coronary artery bypass surgery. Patients w/ history of ischemic heart disease, peripheral arterial disease & cerebrovascular disease; significant risk factors for CV disease eg, HTN, hyperlipidemia & DM.
Drug Interactions
Changes in plasma conc w/ CYP2C9 inhibitors & inducers. Increased plasma conc w/ fluconazole. Drugs metabolised by CYP2D6.
MIMS Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Presentation/Packing
Form
Brexen cap 200 mg
Packing/Price
100's (P2,625/box)
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