Seek medical advice if a previously effective dose no longer gives the same symptomatic relief. Thyrotoxicosis & severe CV disorder eg, ischemic heart disease, tachyarrhythmias or severe heart failure, diabetics. Acute severe asthma. Additional blood glucose controls in diabetic patients. Risk of serious hypokalemia. Regularly check patient's inhalation technique. Monitor serum K levels. Pregnancy & lactation.