Possible symptoms and signs: Headache, anxiety, tremor, nausea, tonic muscle cramps, palpitations, tachycardia and cardiac arrhythmias. A fall in blood pressure sometimes occurs.
Laboratory Findings: Hyperglycemia and lactic acidosis sometimes occur. β2-agonists may cause hypokalemia as a result of redistribution of potassium.
Treatment of overdosage: Usually, no treatment is required. If it is suspected that significant amounts of terbutaline sulfate have been swallowed, the following measures should be considered: Gastric lavage, activated charcoal. Determine acid-base balance, blood glucose and electrolytes.
Monitor heart rate and rhythm, and blood pressure. The preferred antidote for overdosage with Terbutaline sulfate (BRICANYL) is a cardioselective beta-receptor blocking agent, but it should be used with caution in patients with a history of bronchospasm.
If the β2-mediated reduction in peripheral vascular resistance significantly contributes to the fall in blood pressure, a volume expander should be given.
Injection: Preterm Labour: Pulmonary Edema: A normal dose of loop diuretic (eg, furosemide) should be given intravenously. Increased tendency to bleeding in connection with caesarean section: Give propranolol, 1-2 mg intravenously.