The most frequently reported adverse effects with candesartan include back pain, dizziness, upper respiratory tract infection, pharyngitis, and rhinitis.
Blood and lymphatic system disorders:
Agranulocytosis, anemia, eosinophilia, leukocytosis, leukopenia, neutropenia, thrombocytopenia.
Metabolism and nutrition disorders:
Hyperkalemia, hypoglycemia, hyponatremia, thirst.
Nervous system disorders:
Headache, lightheadedness, numbness of limbs, numbness of tongue, sleepiness, syncope, vertigo, abnormal taste.
Atrial fibrillation, bradycardia, extrasystole, palpitation.
Hypotension, shock, hot flushes.
Respiratory, thoracic and mediastinal disorders:
Cough, epistaxis, interstitial pneumonia, sinusitis.
Anorexia, constipation, diarrhea, epigastric pain, gastric ulcer, nausea, stomach discomfort, stomatitis, vomiting.
Abnormal hepatic function, hepatitis, jaundice.
Skin and subcutaneous tissue disorders:
Angioedema, eczema, photosensitivity, pruritus, rash, urticaria.
Musculoskeletal and connective tissue disorders:
Arthralgia, myalgia, rhabdomyolysis.
Renal and urinary disorders:
Renal impairment, renal failure, proteinuria, pollakiuria.
General disorders and administration site conditions:
Edema, fatigue, fever, malaise, lumbar pain, weakness.
Increases in serum potassium, serum creatinine, blood urea nitrogen (BUN), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (γ-GTP), lactic dehydrogenase (LDH), creatinine phosphokinase (CPK), c-reactive protein (CRP), total cholesterol, serum uric acid; decreases in serum total protein, hemoglobin.