Generic Medicine Info
Indications and Dosage
Gastro-oesophageal reflux disease
Adult: 20 mg tid.

Mouth ulceration
Adult: Apply 2% gel 4 times daily.
Hypokalaemia; cardiac failure and in those receiving cardiac glycosides. Pregnancy, elderly, child <3 yrs.
Special Precautions
Cardiac disease, hypertension, impaired hepatic or renal function.
Adverse Reactions
Sodium and water retention, hypokalaemia.
Drug Interactions
Antagonism with amiloride and spironolactone. Exacerbates hypokalaemia associated with diuretics.
Potentially Fatal: Risk of toxicity with digitalis glycosides.
Description: Carbenoxolone is a synthetic derivative of glycyrrhizinic acid (a constituent of liquorice). It acts by protecting the mucosal barrier from acid-pepsin attack and increasing mucosal mucin production.
Absorption: Absobed in the GI tract, mainly from the stomach.
Distribution: Highly bound to plasma proteins.
Excretion: Mainly excreted in the faeces via the bile.
MIMS Class
Antacids, Antireflux Agents & Antiulcerants / Preparations for Oral Ulceration & Inflammation
Disclaimer: This information is independently developed by MIMS based on Carbenoxolone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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