Cardomin Dosage/Direction for Use







Full Prescribing Info
Dosage/Direction for Use
Dobutamine infusion should ideally be started at a low rate of 0.5-1 mcg/kg/min and titrated against patient response at intervals of a few minutes.
Adults: 2.5-15 mcg/kg/min (maximum: 40 mcg/kg/min), titrated to desired response.
Children: 2.5-15 mcg/kg/min titrated to desired response.
Infusions up to 72 hrs have revealed no adverse effects other than those seen with shorter infusions beyond which partial tolerance develops to the drugs.
Administration: Use infusion device to control rate of flow. Administer into large vein.
Management of Extravasation: Inject a small amount of phentolamine solution (5 mg dissolved in 9 mL normal saline) into extravasation area. Blanching should reverse immediately. Monitor the site. If blanching recurs, additional injection of phentolamine may be needed.
Monitoring Parameters: Blood pressure, electrocardiogram (ECG), heart rate, central venous pressure (CVP), right atrial pressure (RAP), mean atrial pressure (MAP), urine output; if pulmonary artery catheter is in place, monitor cardiac index (CI), pulmonary capillary wedge pressure (PCWP) and systemic vascular resistance (SVR); also monitor serum glucose. May affect serum assay of chloramphenicol.
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