HIGHLIGHT
Cefudyne

Cefudyne

cefuroxime

Manufacturer:

Sydenham

Distributor:

Nurturemed
Concise Prescribing Info
Contents
Cefuroxime axetil
Indications/Uses
Bone & joint infections, bronchitis (& other lower resp tract infections), gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis, skin infections (including soft tissue infections) & UTI. Surgical infection prophylaxis.
Dosage/Direction for Use
Adult Most infections, mild to moderate lower resp tract infections (eg, bronchitis), pyelonephritis 250 mg every 12 hr. UTI 125 mg every 12 hr. More severe lower resp tract infections, or if pneumonia is suspected 500 mg every 12 hr. Uncomplicated gonorrhea 1 g as single dose. Ped 3 mth-12 yr Pharyngitis/tonsillitis 20 mg/kg bid divided in equal doses for 10 days. Max: 500 mg/day. Acute bacterial otitis media, acute bacterial maxillary sinusitis (mild to moderate), impetigo 30 mg/kg bid divided in equal doses for 10 days. Max: 1,000 mg/day.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to cefuroxime axetil & other cephalosporins.
Special Precautions
Monitor renal hematological status especially during prolonged & high-dose therapy. Renal impairment. Pregnancy & lactation.
Adverse Reactions
GI disturbances including diarrhea, nausea, & vomiting. Rarely, erythema multiforme, Stevens-Johnson syndrome, & toxic epidermal necrolysis.
Drug Interactions
Reduced renal clearance w/ probenecid. May lower bioavailability w/ drugs which reduce gastric acidity.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Cefudyne powd for oral susp 250 mg/5 mL
Packing/Price
70 mL x 1's
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