Initially 1 drop of 0.25% solution in the affected eye(s) twice a day; maximum 1 drop of 0.5% solution twice a day. If intraocular pressure is maintained at satisfactory levels, patient can be placed on once a day therapy. To transfer to another beta-blocking ophthalmic solution discontinue at the end of a full-day treatment & begin treatment next day. To transfer from single anti-glaucoma agent to other ophthalmic beta-blocker, continue agent already being used and add therapy at an initial of timolol maleate. On the next day discontinue the previously used anti-glaucoma agent.