Patients using anticoagulants (eg, warfarin), platelet aggregation inhibitor including aspirin, ticlopidine & thrombolytics including urokinase & alteplase; prostaglandin E1 or derivative (alprostadile, rimaprodex, alphadex). Patients w/ menstruation. Severe renal impairment (CrCl ≤25 mL/min). Moderate or severe hepatic impairment. Known predisposition to bleeding (eg, active peptic ulceration, haemorrhagic stroke, proliferative diabetic retinopathy, poorly controlled HTN). History of ventricular tachycardia, ventricular fibrillation or multifocal ventricular ectopics; prolongation of QTc interval. Report any episode of bleeding or easy bruising; early development of dyscrasia. May cause dizziness affecting ability to drive or operate machinery. Pregnancy & lactation. Elderly.