Cimex/Cimex Plus

Cimex/Cimex Plus

cefuroxime

Manufacturer:

Multicare

Distributor:

Zuellig
Concise Prescribing Info
Contents
Cefuroxime (tab/susp: axetil; inj: Na)
Indications/Uses
Cimex Treatment of susceptible infections eg, bronchitis, gonorrhea, meningitis, otitis media, peritonitis, pharyngitis, sinusitis; skin, bone & joint infections, UTI. Surgical infection prophylaxis. Cimex Plus Infections due to sensitive gm +ve & gm -ve bacteria; surgical prophylaxis; more active against Haemophilus influenzae & Neisseria gonorrhea; Lyme disease.
Dosage/Direction for Use
Cimex FC tab Adult Pharyngitis/tonsillitis, acute sinusitis 250-500 mg bid. Acute bronchitis, acute exacerbation of chronic bronchitis, skin infections 250-500 mg bid. Uncomplicated gonorrhea 1 g as single dose. Uncomplicated UTI 125 mg or 250-500 mg bid. Cimex oral susp 125 mg/5 mL Adult 5-20 mL (1-4 tsp) bid. Childn >2 yr 10 mL (2 tsp) or 15 mg/kg bid. Max 20 mL daily; >3 mth 5 mL (1 tsp) or 10 mg/kg bid. Max 10 mL (2 tsp) daily. Cimex oral susp 250 mg/5 mL Adult 5-10 mL (1-2 tsp) bid. Childn >2 yr 5 mL (1 tsp) or 15 mg/kg bid. Max 10 mL (2 tsp) daily; >3 mth 2.5 mL (½ tsp) or 10 mg/kg bid. Max 5 mL (1 tsp) daily. Cimex Plus Deep IM inj/slow IV inj over 3-5 min/IV infusion. Adult 750 mg 8 hrly. Severe infections 1.5 g IV 6-8 hrly. Infant & childn 30-60 mg/kg daily, increased to 100 mg/kg daily in 3 or 4 divided doses. Neonates 100 mg/kg daily in 2 or 3 divided doses. Meningitis Adult 3 g IV 8 hrly. Infant & childn 200-240 mg/kg IV daily in 3 or 4 divided doses, may be decreased to 100 mg/kg daily after 3 days or when there is no clinical improvement. Neonates 100 mg/kg daily, decreased to 50 mg/kg daily. Gonorrhea 1.5 g as single IM dose divided between 2 inj sites. Uncomplicated gonorrhea 1 g as single dose given w/ probenecid 1 g. Surgical infection prophylaxis 1.5 g IV prior to procedure, may be supplemented by 750 mg IV or IM 8 hrly for up to 24-48 hr depending upon the procedure. Total joint replacement 1.5 g powd may be mixed w/ methyl methacrylate cement.
Administration
FC tab: May be taken with or without food. Powd for oral susp: Should be taken with food.
Special Precautions
Hypersensitivity. Renal impairment. Pregnancy & lactation. 
Adverse Reactions
GI disturbances (diarrhea, nausea, vomiting), headache. Cimex Plus Pruritus, shivering, exanthema, fever, urticaria, lymph node tumidity, arthrodynia, anaphylactic reaction. Severe renal disorder.
Drug Interactions
Cimex Probenecid. Cimex Plus Furosemide diuretics & aminoglycosides.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Cimex FC tab 500 mg
Packing/Price
50's (P68/film-coated tab)
Form
Cimex powd for oral susp 125 mg/5 mL
Packing/Price
50 mL x 1's (P313.5/bottle);70 mL x 1's (P399/bottle)
/philippines/image/info/cimex powd for oral susp 125 mg-5 ml/125 mg-5 ml x 70 ml?id=2b2ebb75-87ae-4f77-9765-a284009d4cad
/philippines/image/info/cimex powd for oral susp 125 mg-5 ml/125 mg-5 ml x 50 ml?id=d67969ce-5b62-427e-94d2-a284009d4cad
Form
Cimex powd for oral susp 250 mg/5 mL
Packing/Price
50 mL x 1's (P475/bottle)
Form
Cimex Plus powd for inj 750 mg
Packing/Price
1's (P330/powd for inj)
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