In the event of hypersensitivity, which in some instances can occur after the 1st administration, therapy should be discontinued.
Ciprofloxacin should be used with caution in epileptics and patients with a history of CNS disorders and only if the benefits of treatment are considered to outweigh the risk of possible CNS adverse effects. CNS side-effects have been reported after first administration of Ciprofloxacin in some patients. Treatment should be discontinued if the side-effects, depression or psychoses lead to self-endangering behavior.
Crystalluria related to the use of Ciprofloxacin has been reported. Patients receiving Ciprofloxacin should be well hydrated and excessive alkalinity of the urine should be avoided.