Adults ≥18 years: 500 mg twice a day every 12 hrs.
Uncomplicated Acute Gonorrhea: Recommended Dose: 250 mg as single dose.
Meningococcal Meningitis Prophylaxis: 500 mg.
Children and Adolescents: Inhalation of Anthrax: 15 mg/kg twice a day, not to exceed 500 mg twice a day for 60 days.
Patients with renal impairment are given reduced doses with regular monitoring of the plasma concentrations of the drug. If CrCl <20 mL/min, 250 mg oral ciprofloxacin is administered.