Ciptid

Ciptid

ciprofloxacin

Manufacturer:

Stallion Labs

Distributor:

Ambica
Concise Prescribing Info
Contents
Ciprofloxacin
Indications/Uses
Severe infections of urinary & GI tracts including Campylobacter jejuni, shigella or salmonella; susceptible STDs eg, gonococcal (including penicillin-resistant) & nongonococcal (chlamydial urethritis), osteomyelitis/septicemia caused by susceptible organisms including bacteria resistant to β-lactams. Severe infections of the resp tract due to susceptible gm -ve infections including Pseudomonas aeruginosa. Multidrug-resistant TB in combination w/ other drugs. Multidrug-resistant typhoid fever; post-exposure prophylaxis for meningococcal disease & anthrax in adult.
Dosage/Direction for Use
Adult Lower resp tract infections 400 mg bid-tid for 7-14 days. Acute exacerbation of chronic sinusitis & chronic suppurative otitis media 400 mg bid-tid for 7-14 days. Malignant external otitis 400 mg tid for 28 days up to 3 mth. Complicated & uncomplicated pyelonephritis 400 mg bid-tid for 7-21 days & can be continued for >21 days in some specific circumstances. Prostatitis 400 mg bid-tid for 2-4 wk (acute). Epididymo-orchitis & pelvic inflammatory diseases 400 mg bid-tid for at least 14 days. Diarrhoea caused by bacterial pathogens including Shigella spp other than Shigella dysenteriae type 1 & empirical treatment of severe travellers' diarrhoea 400 mg bid for 1 day. Diarrhoea caused by Shigella dysenteriae type 1 400 mg bid for 5 days. Diarrhoea caused by Vibrio cholerae 400 mg bid for 3 days. Typhoid fever 400 mg bid for 7 days. Intra-abdominal infections due to gm -ve bacteria 400 mg bid-tid for 5-14 days. Skin & soft tissue infections 400 mg bid-tid for 7-14 days. Bone & joint infections 400 mg bid-tid for a max of 3 mth. Neutropenic patients w/ fever due to bacterial infection 400 mg bid-tid & should be continued over the entire period of neutropenia; should be administered w/ appropriate antibacterial agent. Inhalation anthrax post-exposure prophylaxis & curative treatment for those requiring parenteral treatment 400 mg bid for 60 days from the confirmation of Bacillus anthracis exposure. Childn Cystic fibrosis 10 mg/kg tid w/ max of 400 mg/dose for 10-14 days. Complicated UTI & pyelonephritis 6-10 mg/kg tid w/ max of 400 mg/dose for 10-21 days. Inhalation anthrax post-exposure curative treatment for those requiring parenteral treatment 10-15 mg/kg bid w/ max of 400 mg/dose for 60 days from the confirmation of Bacillus anthracis exposure. Other severe infections 10 mg/kg tid w/ max of 400 mg/dose. Renal & hepatic impairment CrCl >60 mL/min/1.73 m2 & creatinine >124 μmol/L Usual dose, 30-60 mL/min/1.73 m2 & creatinine 124-168 μmol/L 200-400 mg every 12 hr, >30 mL/min/1.73 m2 & creatinine >169 μmol/L 200-400 mg every 12 hr. Haemodialysis (creatinine >169 μmol/L) 200-400 mg every 12 hr (after dialysis). Peritoneal dialysis (creatinine >169 μmol/L) 200-400 mg every 12 hr.
Contraindications
Hypersensitivity to ciprofloxacin & other quinolones. Tizanidine.
Adverse Reactions
Vomiting, transient increase in transaminases, rash.
Drug Interactions
Probenecid interferes w/ renal secretion. Increased serum conc w/ probenecid. Potentiated hypotensive & sedative effect w/ tizanidine. May inhibit renal tubular transport potentially leading to increased plasma levels of methotrexate & increased risk of methotrexate-associated toxic reactions.
MIMS Class
ATC Classification
J01MA02 - ciprofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Presentation/Packing
Form
Ciptid infusion 200 mg/100 mL
Packing/Price
100 mL x 1's
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