Pharmacology: Pharmacokinetics: Aceclofenac is well-absorbed from the gastro-intestinal tract; peak plasma concentrations are reached 1 to 3 hours after an oral dose. Aceclofenac is more than 99% bound to plasma proteins. The plasma-elimination half-life is approximately 4 hours. About two-thirds of a dose is excreted in the urine, mainly as hydroxymetabolites.