Patients with known hypersensitivity to macrolide antibiotic drugs.
Clariget: Concomitant administration of clarithromycin with any of the following medicines is contraindicated: Astemizole, cisapride, pimozide and terfenadine.
Clariget OD: Patients with creatinine clearance <30 mL/min.
Concomitant administration with the following drugs: Astemizole, pimozide, cisapride, terfenadine, ergotamine or dihydroergotamine.
Clarithromycin in combination with ranitidine bismuth citrate should not be used in patients with a history of acute porphyria.