Antila Lifesciences


AGlobal Care
Concise Prescribing Info
Clobetasol propionate
Short term treatment of more resistant inflammatory & pruritic manifestations of steroid responsive dermatoses unresponsive to less potent corticosteroids eg, psoriasis (excluding widespread plaque psoriasis), recalcitrant dermatoses, lichen planus, discoid lupus erythematosus, other skin conditions which do not respond satisfactorily to less potent steroids for adults, elderly & childn >1 yr.
Dosage/Direction for Use
Adult, elderly & childn >1 yr Apply thinly & gently rub on affected area once daily or bid. Max: Not >50 g/wk. Recalcitrant dermatoses in patients who frequently relapse Intermittent dosing (once daily, twice wkly, w/o occlusion) may be considered & should be combined w/ routine daily use of emollients.
Hypersensitivity. Untreated cutaneous infections, rosacea, acne vulgaris, pruritus w/o inflammation, perianal & genital pruritus, perioral dermatitis. Dermatoses including dermatitis & nappy eruptions in childn <1 yr.
Special Precautions
Local hypersensitivity reactions. Cushing's syndrome & reversible hypothalamic-pituitary-adrenal axis suppression may occur. Abrupt w/drawal of treatment may result in glucocorticosteroid insufficiency. Propylene glycol content may cause skin irritation; cetostearyl alcohol content may cause allergic reactions; chlorocresol content may cause allergic reactions. Increased risk of systemic effects when applied to large surface area, on occluded areas of skin, increasing hydration of the stratum corneum, face application, broken skin or other conditions where the skin barrier may be impaired. Infection risk w/ occlusion. Psoriasis. Concomitant infection. Chronic leg ulcers. Face application (limited to 5 days). If applied to eyelids, ensure that the prep does not enter the eye. Visual disturbance. Pregnancy & lactation. Infants & childn <12 yr.
Adverse Reactions
Pruritus, local skin burning, skin pain.
Drug Interactions
Increased systemic exposure w/ ritonavir & itraconazole.
ATC Classification
D07AD01 - clobetasol ; Belongs to the class of very potent (group IV) corticosteroids. Used in the treatment of dermatological diseases.
Clobila cream 500 mcg/g
10 g x 1's
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