Clotrix

Clotrix

clotrimazole

Manufacturer:

Bal Pharma

Distributor:

Endure Medical
Full Prescribing Info
Contents
Clotrimazole.
Description
Each gram contains: Clotrimazole 10 mg.
Action
Pharmacology: Pharmacokinetics: When applied topically clotrimazole penetrates the epidermis but there is little if any systemic absorption. Absorption of 3 to 10% of a dose has been reported after vaginal use. Clotrimazole is metabolised in the liver to inactive compounds and excreted in the faeces and urine.
Indications/Uses
Used topically in superficial candidiasis, and in the skin infections pityriasis versicolor and dermatophytosis. Clotrimazole may also be used occasionally for symptomatic relief of the protozoal infection trichomoniasis when other drugs are contra-indicated.
Dosage/Direction for Use
Clotrimazole is applied topically two or three times daily for 2 to 4 weeks as a 1% cream, lotion. Or as prescribed by the physician.
Special Precautions
Intravaginal preparations of clotrimazole may damage latex contraceptives and additional contraceptive measures are therefore necessary during local application.
Adverse Reactions
Nausea, vomiting, unpleasant mouth sensations, and pruritus have been reported after the use of oral clotrimazole lozenges. Raised liver enzyme values have also occurred. Local reactions including irritation and a burning sensation may occur in patients treated topically; contact allergic dermatitis has been reported. Gastrointestinal disturbance, elevation of liver enzymes, dysuria, and mental depression has been reported after oral clotrimazole (although this route is no longer used).
Storage
Store at temperatures not exceeding 30°C.
ATC Classification
D01AC01 - clotrimazole ; Belongs to the class of imidazole and triazole derivatives. Used in the topical treatment of fungal infection.
Presentation/Packing
Cream 1% x 20 g x 1's.
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