CM Star Neostigmine Methylsulfate

CM Star Neostigmine Methylsulfate



Omega Lab


CM Star
Concise Prescribing Info
Neostigmine methylsulfate
Myasthenia gravis, antagonist to non-depolarizing neuromuscular blockade, paralytic ileus, post-op distension, urinary retention, paroxysmal supraventricular tachycardia.
Dosage/Direction for Use
Post-op intestinal atony Prophylaxis: 250 mcg. Treatment: 500 mcg SC/IM/slow IV repeated at 4-5 hr interval. Urinary retention Prophylaxis: 250 mcg. Treatment: 500 mcg SC/IM. Continue 0.5 mg at 3 hr interval for at least 5 additional inj. Myasthenia gravis 1 mg IM every hr.
Hypersensitivity. Peritonitis, mechanical intestinal or urinary tract obstruction or doubtful bowel viability.
Special Precautions
Epilepsy, bronchial asthma, bradycardia, recent coronary occlusion, vagotonia, hyperthyroidism, cardiac arrhythmias, peptic ulcer. When large doses are given, simultaneous administration of atropine sulfate is advisable. Hypotension & bradycardia if the effect of gallamine of curare is antagonized.
Adverse Reactions
Nausea, vomiting, diarrhea, abdominal cramps, increased salivation & bronchial secretions, miosis, diaphoresis.  Muscle cramps, fasciculation, weakness.
Drug Interactions
Muscle relaxants eg, suxamethonium. Cyclopropane or halothane anesth. Prolonged bradycardia w/ β-adrenoceptor blocking agents. Antagonized effects w/ aminoglycosides & some anti-arrhythmics eg, quinidine.
MIMS Class
Neuromuscular Disorder Drugs
ATC Classification
N07AA01 - neostigmine ; Belongs to the class of anticholinesterase. Used as parasympathomimetics.
CM Star Neostigmine Methylsulfate soln for inj 500 mcg/mL
10 mL x 10 × 1's
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in