Comxicla Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Co-amoxiclav (amoxicillin & clavulanic acid). Per 625 mg tab Amoxicillin 500 mg, clavulanic acid 125 mg

Indications/Uses

Susceptible infections of lower resp tract infections, otitis media & sinusitis caused by β-lactamase producing strains of H. influenzae & Moraxella (Branhamella) catarrhalis; skin & skin structure infections caused by S. aureus, E. coli & Klebsiella spp & Enterobacter spp.

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Dosage/Direction for Use

Adult & childn >12 yr Mild to moderate infection 325 mg every 8 hr. Severe & resp tract infection 625 mg every 8 hr.

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Overdosage

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Administration

May be taken with or without food: Preferably taken at the start of meals for better absorption & to reduce GI discomfort.

Contraindications

Hypersensitivity to penicillin. History of amoxicillin w/ clavulanic acid-associated cholestatic jaundice/hepatic dysfunction. Mononucleosis.

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Special Precautions

Possibility of superinfections w/ mycotic or bacterial pathogens. Discontinue if superinfections occur.

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Adverse Reactions

Diarrhea, nausea, skin rashes, urticaria, vomiting & vaginitis.

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Drug Interactions

Decreased renal tubular secretion w/ probenecid. Increased & prolonged blood levels of amoxicillin. May reduce efficacy of OCs. May prolong bleeding time w/ anticoagulants.

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Storage

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Description

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Action

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MIMS Class

Penicillins

ATC Classification

J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Comxicla 625 mg tab

Packing/Price

20's;50's

Comxicla

amoxicillin + clavulanic acid

Manufacturer:

Indchemie Health Specialities

Distributor:

Suhitas