Coxid

Coxid

celecoxib

Manufacturer:

Westmont

Distributor:

United Lab
Concise Prescribing Info
Contents
Celecoxib
Indications/Uses
Relief of signs & symptoms of OA, RA & ankylosing spondylitis; juvenile RA in patients ≥2 yr. Management of acute pain including post-op dental or orthopedic pain. Primary dysmenorrhea.
Dosage/Direction for Use
OA 200 mg once daily. RA 100-200 mg bid. Ankylosing spondylitis 200 mg once daily. May be increased to 400 mg once daily if no response after 6 wk. Acute pain & primary dysmenorrhea Initially 400 mg followed by additional dose of 200 mg on 1st day & subsequently, 200 mg bid as needed. Juvenile RA Childn ≥2 yr, 10-25 kg 50 mg bid; >25 kg 100 mg bid.
Administration
May be taken with or without food: Higher doses (eg, 400 mg twice a day) should be taken w/ meals to improve absorption.
Special Precautions
Patients w/ poor CYP2C9 metabolizers. Moderate hepatic impairment. Not recommended use w/ severe hepatic impairment. Renal insufficiency.
Adverse Reactions
Peripheral edema, angina pectoris, chest pain, CAD, MI, palpitation, tachycardia, aggravated HTN, syncope, CHF, ventricular fibrillation, pulmonary embolism, CVA, peripheral gangrene, thrombophlebitis, DVT, vasculitis; dyspepsia, diarrhea, constipation, abdominal pain, nausea, vomiting, flatulence, anorexia, diverticulitis, dry mouth, dysphagia, eructation, esophagitis, gastritis, gastroenteritis, gastroesophageal reflux, hemorrhoids, hiatal hernia, increased appetite, melena, stomatitis, taste perversion, tenesmus, tooth disorder, dry socket, intestinal obstruction, intestinal perforation, GI bleeding, colitis w/ bleeding, esophageal perforation, pancreatitis, cholelithiasis, ileus, intestinal anastomotic ulceration; headache, migraine, dizziness, insomnia, somnolence, anxiety, asthenia, depression, hypertonia, hypoesthesia, nervousness, neuralgia, neuropathy, paresthesia, vertigo, aseptic meningitis, ataxia, ageusia, anosmia, fatal intracranial hemorrhage, suicide; upper resp tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm (including aggravated bronchospasm), coughing, dyspnea, laryngitis, pneumonia, nasopharyngitis; rash, alopecia, dermatitis, dry skin, erythematous rash, maculopapular rash, nail disorder, photosensitivity reaction, pruritus, skin disorder, increased sweating, urticaria; aggravated allergy, bronchospasm, generalized or facial edema, angioedema, anaphylactoid reactions, erythema multiforme, exfoliative dermatitis, Sweet's syndrome, Stevens-Johnson Syndrome, toxic epidermal necrolysis; anemia, ecchymosis, epistaxis, thrombocythemia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, thrombocytopenia; albuminuria, cystitis, dysuria, hematuria, frequent micturition, renal calculus, urinary incontinence, UTI, dysmenorrhea, genital moniliasis, menstrual disorder, vag hemorrhage, vaginitis, prostatic disorder, acute renal failure, interstitial nephritis, renal papillary necrosis, renal injury; borderline elevations in serum ALT (SGPT) or AST (SGOT), jaundice, hepatitis, fatal fulminant hepatitis, liver necrosis, liver failure; back pain, arthralgia, arthrosis, bone disorder, leg cramps, myalgia, neck stiffness, synovitis, tendinitis, accidental fracture; blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, deafness, ear abnormality, earache, otitis media, tinnitus; increased BUN, CPK, nonprotein nitrogen, creatinine & alkaline phosphatase; DM, hyperglycemia, hypoglycemia, hypercholesterolemia, hypokalemia, hyponatremia, wt gain; hot flushes, accidental injury, cysts, fatigue, fever, flu-like symptoms, soft tissue infection, bacterial & fungal infections (including moniliasis), viral infections (including herpes simplex or herpes zoster), pain & peripheral pain, sepsis, sudden death.
ATC Classification
M01AH01 - celecoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.
Presentation/Packing
Form
Coxid cap 400 mg
Packing/Price
30's
Form
Coxid cap 200 mg
Packing/Price
30's
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