Daisy-30 Mechanism of Action

desogestrel + ethinylestradiol


Mylan Phils


Metro Drug
Full Prescribing Info
Pharmacotherapeutic Group: Hormonal contraceptive.
Pharmacology: Pharmacodynamics:
Daisy-30 is an oral contraceptive combination containing 150 micrograms desogestrel and 30 micrograms ethinylestradiol.
Ethinylestradiol is a well known synthetic estrogen.
Desogestrel is a synthetic progestogen. After oral administration it has a strong ovulation-inhibiting activity, a strong progestational and anti-estrogenic activity, no estrogenic activity, very weak androgenic/anabolic activity.
Pharmacokinetics: After oral administration, desogestrel shows rapid absorption, followed by distribution throughout the body, and subsequent excretion, not resulting in retention of the drug and/or its metabolites. The freely extractable fraction in serum of volunteers contains desogestrel, 3-keto-desogestrel and polar metabolites.
The level of the unchanged drug decreases rapidly and the level of the biologically active 3-keto-metabolite is still measurable 24 hours after dosing.
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