Akums Drug


Concise Prescribing Info
Levofloxacin hemihydrate
Susceptible infections including TB, uncomplicated/complicated UTI, chronic bacterial prostatitis, complicated skin infections, hospital-/community-acquired pneumonia, acute bacterial sinusitis, acute pyelonephritis. Treatment & post exposure prophylaxis of inhalation anthrax.
Dosage/Direction for Use
IV infusion Uncomplicated UTI 250 mg once daily for 3 days. Most susceptible infections 250 or 500 mg once daily or bid for 10-14 days. Chronic bacterial prostatitis 500 mg once daily for 28 days. Complicated skin infections & hospital-acquired pneumonia Alternatively, 750 mg once daily for 7-14 days. Community-acquired pneumonia or acute bacterial sinusitis 750 mg once daily for 5 days.
Special Precautions
Patients w/ epilepsy or history of CNS disorders. Discontinue if patients experience tendon pain, inflammation or rupture. Patients w/ G6PD deficiency or myasthenia gravis. Avoid use in MRSA infection. Maintain adequate fluid intake & avoid excessive urine alkalinity. Avoid exposure to strong sunlight or sunlamps. Prolonged QT interval (isolated cases). May impair ability to drive or operate machinery. Impaired hepatic or renal function. Pregnancy & lactation. Childn & adolescents.
Adverse Reactions
Nausea, vomiting, diarrhea, abdominal pain, dyspepsia; headache, dizziness, restlessness. Tremor, drowsiness, insomnia, nightmares, visual & sensory disturbances.
Drug Interactions
May inhibit hepatic metabolism & interfere clearance of drugs eg, theophylline. Reduced absorption w/ cations eg, Al, Mg or Fe. Pharmacokinetic changes w/ H2 antagonists.
MIMS Class
ATC Classification
J01MA12 - levofloxacin ; Belongs to the class of fluoroquinolones. Used in the systemic treatment of infections.
Diafloxcin soln for infusion 5 mg/mL
100 mL x 1's
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