May adversely affect blood sugar control w/ thiazide diuretics, barbiturates, glucocorticoids & estrogens. Increased risk of hypoglycemia w/ insulin, biguanides, sulphonamides, oxyphenbutazone, phenylbutazone, clofibrate, salicylates, coumarin derivatives, chloramphenicol, MAOIs, β-blockers, cimetidine, ethanol, miconazole (systemic route, oromucosal gel), phenylbutazone (systemic route), alcohol. Potentiation of blood glucose lowering effect w/ other antidiabetic agents (insulins, acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, GLP-1 receptor agonists), β-blockers, fluconazole, ACE inhibitors (captopril, enalapril), H2
antagonists, MAOIs, sulphonamides, clarithromycin & NSAIDs. Increased risk of hyperglycemia w/ danazol, chlorpromazine (neuroleptic agent), glucocorticoids (systemic & local route); & ritodrine, salbutamol, terbutaline (IV). Potentiation of anticoagulation during concurrent treatment of warfarin.