Diethylamine salicylate


Generic Medicine Info
Indications and Dosage
Topical/Cutaneous
Musculoskeletal pain
Adult: As 10% w/w cream: Apply onto the affected area 2 or 3 times daily. Use sparingly.
Child: ≥6 years Same as adult dose.
Contraindications
Hypersensitivity to diethylamine salicylate, aspirin, or other NSAIDs (including oral hypersensitivity) particularly when associated with history of asthma. Application on broken, abraded, or cut skin.
Special Precautions
Patient with asthma. Children. Pregnancy and lactation.
Adverse Reactions
Skin and subcutaneous tissue disorders: Temporary skin reactions (e.g. rashes, redness, discomfort, irritation, burning sensation).
Patient Counseling Information
Avoid contact with eyes and sensitive skin areas.
Drug Interactions
May enhance the anticoagulant effects of warfarin. May increase the blood concentrations and risk of toxicity of methotrexate.
Action
Description: Diethylamine salicylate is a salicylic acid derivative topical analgesic. It has the anti-inflammatory effects of salicylates and may be used as a counterirritant.
Pharmacokinetics:
Absorption: Absorbed through the skin (small amounts as salicylic acid).
Excretion: Via urine.
Chemical Structure

Chemical Structure Image
Diethylamine Salicylate

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 9837223, Diethylamine salicylate. https://pubchem.ncbi.nlm.nih.gov/compound/Diethylamine-salicylate. Accessed Oct. 26, 2020.

Storage
Store below 25°C.
References
Algesal Cream (Thornton & Ross Limited). MHRA. https://products.mhra.gov.uk/. Accessed 02/10/2020.

Anon. Diethylamine Salicylate. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 02/10/2020.

Buckingham R (ed). Diethylamine Salicylate. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 02/10/2020.

Odour Free Lloyds Cream (Thornton & Ross Limited). MHRA. https://products.mhra.gov.uk/. Accessed 02/10/2020.

Disclaimer: This information is independently developed by MIMS based on Diethylamine salicylate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by MIMS.com
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