Differin Dosage/Direction for Use





Full Prescribing Info
Dosage/Direction for Use
Gel 0.1% and Cream: Differin Gel and Differin Cream should be applied to the acne affected areas once a day before retiring and after washing. A thin film of the product should be applied avoiding the eyes and lips (see Precautions). Ensure that the affected areas are dry before application.
With patients for whom it is necessary to reduce the frequency of application or to temporarily discontinue treatment, frequency of application may be restored or therapy resumed once it is judged that the patient can again tolerate the treatment.
If patients use cosmetics, these should be non-comedogenic and non-astringent.
The safety and effectiveness of Differin Gel and Differin Cream have not been studied in neonates and young children.
Gel 0.3%: Adapalene (Differin) 0.3% gel should be applied to the affected areas of the face, chest and back once a day before retiring and after washing. A small amount should be applied to provide a thin film, avoiding eyes, lips and mucous membranes. This medication should not be applied to cuts, abrasions, eczematous, or sunburned skin.
Discontinue treatment if a severe local inflammatory response is experienced. Reinstitute therapy when the reaction has subsided, initially applying the preparation less frequently. Once daily application may be resumed if it is judged that the patient is able to tolerate the treatment.
Clinical improvement is expected to be clearly evident after four to eight weeks of treatment, with further improvement expected with continued use. Cutaneous safety of Adapalene (Differin) 0.3% gel has been demonstrated over a 12-month period of treatment.
Missed Dose: Dosing should continue as per usual the following evening, and the usual amount should be applied.
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