There are no known cases of overdosage with Difflam lozenges and throat spray. Adverse central nervous system (CNS) effects have been reported following overdosage with high doses of Difflam solution. Difflam is unlikely to cause adverse systemic effects, even if accidental ingestion should occur.
There is no specific antidote for benzydamine and should excessive quantities be ingested, the treatment should be symptomatic. Excess consumption of products containing isomalt may have a laxative effect.