80 or 160 mg once daily. May be increased to 320 mg once daily or add another antihypertensive (eg, diuretic) if BP reduction is inadequate. Heart failure
Initially 40 mg bid, up-titrated to 80 & 160 mg bid as tolerated. Max: 320 mg daily in divided doses. Post-MI
Initially 20 mg bid, up-titrated to a max of 160 mg bid as tolerated. Hypertensive patient w/ IGT at CV risk Progression of type 2 diabetes
80 or 160 mg once daily. When started on 80 mg, up-titrate to 160 mg as tolerated. Childn & adolescent 6-18 yr HTN
Initially 40 mg (<35 kg) or 80 mg (≥35 kg) once daily.