Adult Epilepsy Initially 600 mg in 2 divided doses. May be increased by 200 mg every 3 days to a usual range of 1-2 g daily, up to max of 2.5 g daily.
Acute manic episodes of bipolar disorder Initially 750 mg in 2 or 3 divided doses, may be increased to 20-30 mg/kg daily, max up to 60 mg/kg daily.
Prophylaxis of migraine 250 mg bid up to 1 g daily.
Childn weighing >20 kg 40 mg daily in 2 divided doses, gradually increased to 20-30 mg/kg daily up to max of 35 mg/kg daily,
<20 kg 20 mg/kg daily in 2 divided doses, may be increased to 40 mg/kg daily or more if necessary.
Neonate Initially 20 mg/kg once daily. Maintenance: 10 mg/kg bid,
1 mth-12 yr Initially 5-7.5 mg/kg bid. Maintenance: 12.5-15 mg/kg bid.
Infantile spasms Up to 30 mg/kg bid,
<12 yr Usual adult dose.
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