Dolowin Plus

Dolowin Plus

aceclofenac + paracetamol


Brown & Burk Phils


Brown & Burk Phils
Concise Prescribing Info
Aceclofenac 100 mg, paracetamol 500 mg
Pain & inflammation in OA, RA, ankylosing spondylitis; low back pain, dental & gynecological pains & inflammatory conditions of ENT.
Dosage/Direction for Use
1 tab (morning & evening). Max: 2 tab a day.
May be taken with or without food.
Hypersensitivity to aspirin & other NSAIDs. Active or suspected peptic ulcer, GI bleeding or bleeding disorder, severe heart failure, HTN, hepatic or renal impairment. Pregnancy.
Special Precautions
Dizziness. Regular monitoring of renal/liver function & complete blood count for individuals receiving long-term treatment. Hepatic porphyria, coagulation disorder, history of peptic ulcer, ulcerative colitis, Crohn's disease, cerebrovascular bleeding. Hypovolemia in patients on diuretic therapy. Mild to moderate impairment of the cardiac, hepatic or renal function in the elderly. Avoid driving or operating machinery. Pregnancy & lactation.
Adverse Reactions
GI disturbances (dyspepsia, abdominal pain, nausea & diarrhoea).
Drug Interactions
Aceclofenac: Increase plasma conc of lithium, digitoxin & methotrexate. May inhibit activity of diuretics. Enhance anticoagulant activity. Convulsion may occur w/ quinolones. Increased incidence of side effects w/ corticosteroids. Paracetamol: May increase risk of paracetamol toxicity in patients receiving potentially hepatotoxic drugs or drugs that induce hepatic microsomal enzymes. Increased absorption w/ rifampicin, INH, chloramphenicol, antiepileptic & antiviral drugs, metoclopramide. Altered plasma conc w/ probenecid. Reduced absorption w/ cholestyramine.
ATC Classification
N02BE51 - paracetamol, combinations excl. psycholeptics ; Belongs to the class of anilide preparations. Used to relieve pain and fever.
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