Doxofix

Doxofix

doxofylline

Manufacturer:

UNILAB, Inc

Distributor:

UNILAB, Inc
Concise Prescribing Info
Contents
Doxofylline
Indications/Uses
Bronchial asthma, pulmonary disease w/ spastic bronchial component & COPD.
Dosage/Direction for Use
Adult 1 tab bid-tid. Elderly ½ tab bid-tid.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Acute MI, hypotension. Lactation.
Special Precautions
Increased t½ & decreased clearance in patients w/ liver disease, CHF, chronic obstructive lung disease or concomitant infections. Hyperthyroidism; hypoxemia; peptic ulcer; renal or hepatic disease; CV disorders including cardiac arrhythmias, angina pectoris, acute myocardial injury, HTN or CHF. Pregnancy & lactation. Children. Elderly.
Adverse Reactions
Nausea, vomiting, epigastric pain, headache, irritability, insomnia, tachycardia, extrasystole, tachypnea & occasionally hyperglycemia & albuminuria.
Drug Interactions
Do not concomitantly administer w/ other methylxanthines including beverages & foods containing caffeine. Increased t½ & decreased clearance w/ cimetidine, allopurinol, propranolol, erythromycin, troleandomycin, lincomycin, ciprofloxacin & anti-flu vaccine. Decreased t½ & increased clearance by phenytoin, anticonvulsants & smoking. Synergistic toxicity w/ ephedrine & other sympathomimetics. May potentiate hypokalemia caused by hypoxia or associated w/ β2-adrenoceptor stimulants (β2-agonist), corticosteroids & diuretics.
ATC Classification
R03DA11 - doxofylline ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.
Presentation/Packing
Form
Doxofix tab 400 mg
Packing/Price
50's
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