Doxorubicin (liposomal) is a special formulation of Doxorubicin in which it is enclosed in a fatty coating. This helps to deliver more medicine to cancer tissue rather than to healthy tissue.
This medicine is used on its own or together with other medicines to treat certain types of cancer.
Doxorubicin (liposomal) may also be used to treat other conditions as decided by your doctor.
Doxorubicin (liposomal) is given intravenously (into the vein) via a drip. It is delivered directly into the bloodstream via the blood vessel.
Your doctor or nurse will administer this medicine to you.
Before the drip is started, you may be given other medicines to prevent or lessen the side effects of Doxorubicin (liposomal). These medicines may be given as tablets or as injections.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Doxorubicin (liposomal).
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Do not use Doxorubicin (liposomal) if you are pregnant or planning to have a baby soon. If you become pregnant while on this medicine, alert your doctor immediately. Doxorubicin (liposomal) may cause harm to your unborn child. Both men and women must use proven birth control methods while being treated with this medicine. You may wish to discuss birth control methods with your doctor. Avoid pregnancy for at least six (6) months after you stop taking this medicine.
Do not breastfeed while you are being treated with this medicine.
Inform your doctor if you have the following conditions:
- liver disease
- kidney disease
- previous chest radiotherapy
Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.
If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking this medicine.
Keep your appointments with your doctor. Your doctor may need to do routine tests (e.g. complete blood count, liver function tests) while you are being treated with this medicine. Your doctor may also need to perform tests to make sure that heart function is normal before you use Doxorubicin (liposomal)and thereafter depending on your doctor’s advice.
Doxorubicin (liposomal) may cause drowsiness, dizziness or blurred vision. If affected, do not drive or take part in any activity in which you need to be alert or to see clearly.
Other side effects may include any of the following: headache, difficulty in sleeping, nervousness, weakness, numbness, nosebleed, nausea, vomiting, diarrhoea, constipation, stomach pain or discomfort, mouth pain or sores, loss of appetite, weight loss, red coloured urine, pain during urination, breast pain, absence of menstrual periods, rash, hair loss, discolouration of skin and nails, muscle or bone pain.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swollen mouth or eyes
- severe mouth pain or sores
- flushing, headache, dizziness, chills or back pain
- breathlessness, chest pain, irregular heartbeat, swelling of your feet or ankles
- painful, reddened skin or sores on your hands or feet
- frequent and persistent sore throat with fever, unusual bleeding or bruising
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor or pharmacist if you are taking any of these medicines:
- other medicines to treat cancer e.g. cyclophosphamide, mercaptopurine, paclitaxel, streptozocin
- medicines to treat epilepsy (fits or seizures) e.g. phenobarbital, phenytoin
- medicines to treat certain heart diseases e.g. verapamil
- blood-thinning medicines e.g. warfarin
- medicines for organ transplant and certain immune disorders e.g. ciclosporin
This list does not include all medicines that may interact with Doxorubicin (liposomal).
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Store in a refrigerator between 2 to 8°C. Do not freeze. Keep away from the reach of children.
Medicines must not be used past the expiry date.