Body as a whole:
Chills and fever, fatigue, asthenia, face edema.
Nausea and vomiting, disturbances of appetite, diarrhea.
Headache, nervousness, agitation, visual disturbances, insomnia, anxiety, dizziness.
Urinary tract infection, sexual dysfunction, painful menstruation.
Dyspnea, bronchitis. Infrequent: Asthma, hiccup, hyperventilation.
Acne, alopecia, dry skin, eczema.
Back pain, joint pain, muscle pain.
It is important to emphasize that all those undesirable effects may also be symptoms of the depression itself and therefore may often decrease during the course of therapy.
Mania/hypomania have been reported in about 1% of patients. Additionally there are reports regarding the activation of mania or hypomania in patients with severe affective disorders treated with other tricyclic antidepressants.
There are few reports about poor concentration, dyspnoea, decreased libido, micturition difficulties.
Leukopaenia or an increase of liver enzymes has been rarely observed.
Hyperprolactinaemia or thrombocytopaenia have been reported in frequently. No casual relationship with fluoxetine therapy has been proven.