For constipation, bisacodyl is given in usual doses of 5 to 15 mg daily as enteric-coated tablets administered at night or 10 mg suppository or enema administered in the morning. Doses of 10 up to 20 mg are given by mouth for complete bowel evacuation, followed by 10 mg as suppository the next morning.
Children under 10 years age may be given 5 mg rectally in the morning for constipation; those over 4 years may alternatively be given 5 mg by mouth at night. For bowel evacuation the dose is 15 mg by mouth the night before and 5 mg rectally the morning of the procedure. Children over 10 years of age may be given doses similar to those for adults.
Bisacodyl has been administered with a barium sulfate enema before radiographic examination of the colon. A complex of bisacodyl with tannic acid is generally used in a dose equivalent to 1.5 to 3 mg of bisacodyl dissolved in 1 liter of barium sulfate suspension. The total dose for one procedure should not exceed 4.5 mg bisacodyl and no more than 6 mg should be administered in 72 hours.
Directions for use: 1. Wash hands thoroughly before and after insertion of Bisacodyl suppository.
2. Clean the area around the rectum with mild soap and warm water, and rinse thoroughly. Gently dry by patting or blotting with toilet issue or soft cloth.
3. Detach one suppository from the strip and hold the suppository in an upright position and carefully peel the wrapper evenly on both sides. Avoid excessive handling as the suppository is designed to melt at body temperature.
4. Position the patient flat on back or on one side with anal opening exposed.
5. Gently insert the suppository well in to the rectum; use fingertip to complete insertion.
6. If necessary, hold the buttocks together for 30-60 seconds to keep suppository in place.
7. If suppository is soft, hold the wrapper under cold water for solidification and then use the suppository.