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Duphalac/Duphalac Fruit

Duphalac/Duphalac Fruit

lactulose

Manufacturer:

Abbott

Distributor:

Abbott
Concise Prescribing Info
Contents
Lactulose
Indications/Uses
Constipation: Regulation of physiological rhythm of the colon; where a soft stool is considered of medical benefit (hemorrhoids, post colonic/anal surgery). Hepatic encephalopathy: Treatment & prevention of hepatic coma or precoma. Prebiotic: Helps create & maintain a healthy intestinal balance & stimulates intestinal absorption of minerals like Ca & Mg (adults). Duphalac Bowel cleansing in prep for colonoscopy (adults).
Dosage/Direction for Use
Adult & adolescent Starting dose: 15-45 mL daily. Maintenance dose: 15-30 mL daily. Childn 7-14 yr Starting dose: 15 mL daily. Maintenance dose: 10-15 mL daily, 1-6 yr Starting & maintenance dose: 5-10 mL daily. Infant <1 yr Starting & maintenance dose: Up to 5 mL daily. During therapy w/ laxatives it is recommended to drink sufficient amounts of fluids (1.5-2 L, equal to 6-8 glasses) during the day. Hepatic encephalopathy Adult Starting dose: 20-30 g or 30-45 mL tid to qid. Prebiotic Adult 7.5-15 mL (corresponding to 5-10 g/day) daily. Duphalac Bowel cleansing Adult Course of treatment consists of bisacodyl 10 mg in the evening before exam & Duphalac soln 1 L 6 hr before colonoscopy (eg, 1 hr after a light breakfast on the day of exam). Dilute soln in order to obtain 12.5% lactulose soln by diluting 200 mL in 800 mL of water or lemon juice.
Administration
May be taken with or without food: Swallow dose immediately, do not keep in mouth for an extended period of time. For single daily dose, take at the same time eg, during breakfast.
Contraindications
Hypersensitivity. Galactosemia. GI obstruction, digestive perforation or risk of digestive perforation. Duphalac Bowel cleansing: Not to be administered to unconscious patients or those w/ impaired consciousness & patients prone to aspiration or regurgitation, general weakness, w/ severe dehydration or impaired swallowing reflex.
Special Precautions
Painful abdominal symptoms of undetermined cause. Treatment of hepatic encephalopathy on diabetics. Chronic use of unadjusted doses & misuse can lead to diarrhea & electrolyte balance disturbance. Lactose, galactose & fructose intolerance, Lapp or total lactase deficiency or glucose-galactose malabsorption. Childn w/ hepatic encephalopathy.
Adverse Reactions
Diarrhea. Flatulence, abdominal pain, nausea, vomiting.
MIMS Class
Cholagogues, Cholelitholytics & Hepatic Protectors / Laxatives, Purgatives
ATC Classification
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Presentation/Packing
Form
Duphalac Fruit syr 3.3 g/5 mL
Packing/Price
((plum aroma flavor)) 200 mL x 1's; ((plum aroma flavor)) 500 mL x 1's
Form
Duphalac syr 3.3 g/5 mL
Packing/Price
((plain flavor)) 120 mL x 1's (P434.77/bottle); ((plain flavor)) 45 mL x 1's (P180.78/bottle)
/philippines/image/info/duphalac syr 3-3 g-5 ml/3-3 g-5 ml x 45 ml?id=c9b2af0b-7bd9-4109-bcec-aae800a9d0cf
/philippines/image/info/duphalac syr 3-3 g-5 ml/3-3 g-5 ml x 120 ml?id=1002fe2f-2549-4195-91dc-aae800a9d0cf
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