Efrox

Efrox

cefuroxime

Manufacturer:

Biopharma

Distributor:

Starpharm

Marketer:

JF Draf
Concise Prescribing Info
Contents
Cefuroxime axetil
Indications/Uses
Treatment of bone & joint, upper & other lower resp tract, skin & soft tissue infections; genito-urinary tract infections, gonorrhea, early Lyme disease & subsequent prevention of late-Lyme disease. Surgical infection prophylaxis.
Dosage/Direction for Use
Uncomplicated UTI 125 mg bid. Resp tract infections 250-500 mg bid. Childn >3 mth 125 mg bid or 10 mg/kg bid to a max of 250 mg daily. Childn >2 yr (w/ otitis media) 250 mg bid or 15 mg/kg bid to a max of 500 mg daily. Uncomplicated gonorrhea 1 g as single dose. Concomitant probenecid 1 g may be administered.
Administration
Tab: May be taken with or without food. Powd for oral susp: Should be taken with food.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
GI disturbances may occur, & rarely, erythema multiforme including Stevens-Johnson syndrome & epidermal necrolysis. Pregnancy (1st trimester) & lactation.
Adverse Reactions
GI disturbances including diarrhea, nausea & vomiting, erythema multiforme, Stevens-Johnson syndrome & toxic epidermal necrolysis.
Drug Interactions
Reduced renal clearance w/ probenecid.
MIMS Class
Cephalosporins
ATC Classification
J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Efrox tab 500 mg
Packing/Price
24's
Form
Efrox powd for oral susp 125 mg/5 mL
Packing/Price
70 mL x 1's
Form
Efrox powd for oral susp 250 mg/5 mL
Packing/Price
50 mL x 1's
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