Endclav-625 Mechanism of Action

amoxicillin + clavulanic acid




Full Prescribing Info
Pharmacology: Pharmacodynamics: Mechanism of Action: Co-Amoxiclav is a novel concept in antibiotic therapy. Resistance to many antibiotics is caused by bacterial enzymes which destroy the antibiotic before it can act on the pathogen. The Clavulanate anticipates this defense mechanism by blocking the β-lactamase enzymes, thus rendering the organisms sensitive to amoxicillin's rapid bactericidal effect of concentrations readily attainable in the body. Clavulanate by itself has little antibacterial activity, however, in association with amoxicillin it produces a novel antibiotic agent of broad spectrum with wide application in hospital and general practice.
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