Pharmacology: Pharmacokinetics: Gabapentin is absorbed from the gastrointestinal tract by means of a saturable mechanism. After multiple dosing peak plasma concentrations are usually achieved within 2 to 3 hours of a dose and steady state achieved within 1 to 2 days. Gabapentin is not appreciably metabolized and most of a dose is excreted unchanged in the urine with the remainder appearing in the faeces. Gabapentin is widely distributed throughout the body but binding to plasma proteins is minimal. The elimination half-life has been reported to be about 5 to 7 hours. Gabapentin is distributed into breast milk.