Chronic renal failure IV/SC Adult
50-100 IU/kg 3 times wkly, childn
25-50 IU kg 3 times wkly. Correction phase: 50 IU/kg 3 times wkly. Adjust dose in increments of 25 IU/kg 3 times wkly at intervals of at least 4 wk until target Hb conc achieved. Maintenance phase: total wkly dose is 75-300 IU/kg. Treatment of anemia in adult cancer patient SC
Initially 150 IU/kg 3 times wkly. Increase dose to 300 IU/kg 3 times wkly if Hb increase is <1 mg/dL and reticulocyte count increased <40,000 cells/μL. Adult surgery patient in an autologous predonation program IV
300-600 IU/kg twice wkly for 3 wk. Elective surgery in adult patient SC
600 IU kg for 3 wk (days 21, 14 & 7) prior & the day of surgery. If shortened surgery of <3 wk, administer 300 IU/kg daily for 10 consecutive days prior & on the day of surgery, & 4 days post-surgery.