It is given orally as the oxalate although doses are expressed in term of the basic,escitalopram oxalate 12.8 mg is equivalent to about 10 mg of escitalopram.
In the treatment of depression: Selective serotonin reuptake inhibitors (SSRI) such as Escitalopram are widely used as an alternative to the older tricyclic as they are fewer adverse effects and are safer in overdosage. The usual dose is 10 mg once daily increased, after at least a week, to a maximum of 20 mg once daily if necessary.
In the treatment of Anxiety Disorders: Escitalopram has been given in anxiety disorders including generalized anxiety disorder, panic disorder, obsessive compulsive disorder and social anxiety disorder, phobic disorders. Doses used in the treatment of anxiety disorders are similar to those used in depression.
Administration in hepatic impairment: Patients with mild to moderate hepatic impairment or those who are poor metaboliser with respect to cytochrome P450 isoenzyme CYP2C19 should receive an initial oral dose of 5mg daily increase to 10 mg daily after 2 weeks depending on response; more careful dose titration is advise in those with sever impairment.