Concise Prescribing Info
Contents
Cefazolin Na
Indications/Uses
Treatment of a variety of infections due to susceptible organisms including biliary tract infections, endocarditis (staphylococcal), endometritis (prophylaxis at caesarian section), peritonitis (associated by continuous ambulatory peritoneal dialysis) & prophylaxis for surgical infections.
Dosage/Direction for Use
Adult 0.5-1 g 6-12 hrly. Max: 6 g daily. Prophylaxis for infections during surgery 0.5 g 1 hr pre-op then 0.5 g during surgery, total dose of 1 g. Then 0.5-1 g 6-8 hrly daily for 5 days for post-op prophylaxis. Childn >1 mth 25-50 mg/kg daily in divided doses & may increased to 100 mg/kg in severe infections. Newborn 20 mg/kg 12 hrly. Doses are given by slow IM or IV inj over 3-5 or by IV infusion.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
Penicillin-allergic patients; renal impairment. Avoid prolonged use. Pregnancy & lactation.
Adverse Reactions
GI disturbances & hypersensitivity. Allergic reactions eg, urticaria, pruritus, exfoliative dermatitis, morbiliform eruptions, rashes, drug fever, chills, serum sickness & eosinophilia.
Drug Interactions
Probenecid, potent diuretics eg, ethacrynic acid & furosemide, aminoglycosides eg, gentamicin & vancomycin; alcohol; heparin, oral anticoagulants & other hemostasis-affecting drugs.
MIMS Class
ATC Classification
J01DB04 - cefazolin ; Belongs to the class of first-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Fazonil powd for inj 500 mg
Packing/Price
(+ 5 mL diluent) 1's;10 × 1's
Form
Fazonil powd for inj 1 g
Packing/Price
(+ 10 mL diluent) 10 × 1's; (+ 10 mL diluent) 1's
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