Generic Medicine Info
Indications and Dosage
Benign prostatic hyperplasia
Adult: 5 mg once daily for at least 6 mth.

Male pattern baldness
Adult: 1 mg once daily for at least 3 mth.
May be taken with or without food.
Women, childn and adolescents. Pregnancy and lactation.
Special Precautions
Men at risk of obstructive uropathy. Hepatic impairment.
Adverse Reactions
Sexual dysfunction (e.g. decreased libido, erectile dysfunction, ejaculation disorders including reduced vol of ejaculate), gynaecomastia, testicular pain, hypersensitivity reactions (e.g. swelling of lips and face, pruritus, urticaria, rashes, angioedema); decreased prostate-specific antigen (PSA) levels; depression, male breast cancer, orgasm disorders.
Patient Counseling Information
Women who are or may become pregnant should avoid contact w/ crushed or broken tablets.
Monitor prostate-specific antigen (PSA) levels.
Lab Interference
May mask serum markers (PSA) for prostate cancer.
Description: Finasteride is a synthetic 4-azasteroid compound and a competitive inhibitor of both tissue and hepatic 5α-reductase. This results in inhibition of the conversion of testosterone to dihydrotestosterone and markedly suppresses serum dihydrotestosterone (DHT) levels. In male pattern baldness, finasteride decreases scalp DHT levels to levels found in hairy scalp. Reduced serum DHT, increases hair regrowth and slows hair loss.
Absorption: Absorbed from the GI tract. Bioavailability: Approx 80%. Time to peak plasma concentration: 1-2 hr.
Distribution: Crosses the blood-brain barrier and distributed into seminal fluid. Volume of distribution: 76 L. Plasma protein binding: Approx 90%.
Metabolism: Undergoes hepatic metabolism primarily by CYP3A4 isoenzyme.
Excretion: Via urine (39%) and faeces (57%) as metabolites. Terminal half-life: Approx 6 hr.
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Finasteride, CID=57363, (accessed on Jan. 21, 2020)

Store at 20-25°C. Protect from light.
Anon. Finasteride. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. Accessed 12/11/2014.

Anon. Finasteride. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 12/11/2014.

Buckingham R (ed). Finasteride. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 12/11/2014.

Finasteride Tablet, Film-coated (Accord Healthcare, Inc.). DailyMed. Source: U.S. National Library of Medicine. Accessed 12/11/2014.

Disclaimer: This information is independently developed by MIMS based on Finasteride from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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